A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Old tuberculin
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A heat-concentrated filtrate of the medium in which tubercle bacilli had been grown. It was produced by Robert Koch in 1891 who, on the basis of the Koch phenomenon, claimed that it would be an effective treatment for tuberculosis. After safety tests on Hedwig Freiberg, a 17 year old art student (who later became Mrs Robert Koch), it was introduced into clinical practice but soon abandoned owing to disappointing results and a few fatalities due to ‘tuberculin shock’. It was, however, used as the basis for the tuberculin test by the Austrian physician Clemens von Pirquet in 1907.
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| Open tuberculosis |
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Infectious tuberculosis with microscopically detectable acid-fast bacilli in the sputum.
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| Outcome (treatment/episode) |
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There are a number of outcomes as a result of treatment. These can be divided into:
1. Cure
2. Satisfactory completion of treatment.
3. Death.
4. Failure to cure
5. Relapse
6. Transfer out (to another treatment centre)
7. Default (the patient is lost to follow up before treatment is completed
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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
